Novi korona virus - velika opasnost ili ne ? POGLEDATI PRVI POST!

[omar little]

Clinical trials happening globally to halt COVID-19

The world is facing one of most serious viral outbreaks in recent memory, COVID-19. Since it was first detected in Wuhan City, China in December, 2019, the virus has spread to over 75 countries, affecting more than 95,000 people and leading to more than 3,200 fatalities globally — the vast majority on mainland China.

COVID-19 is caused by a novel virus within the coronavirus family that has been named severe acute respiratory syndrome coronavirus 2, shortened to SARS-CoV-2. As the name suggests, SARS-CoV-2 is related to, but different from, the virus that caused an outbreak of SARS in 2002-2003. Its long incubation period, estimated to be between two and fourteen days, can make it difficult to detect and contain.

While countries, including Canada, are working hard to contain the virus, keeping the public informed and caring for those who have contracted it, there are currently no specific antiviral treatments for COVID-19.

Clinical trials underway worldwide

How do you contain an outbreak with no known vaccine? The world is turning to clinical trials to find the answer. The World Health Organization (WHO) is compiling the latest scientific findings and knowledge on coronavirus disease (COVID-19) into a database. As of March 5, 2020, it included nearly 1,200 publications from around the world.

China, in particular, has seen a major spike in clinical trial activity in its efforts to develop a treatment, with more than 260 studies registered in the World Health Organization (WHO) International Clinical Trials Registry platform for COVID-19 (as of March 5, 2020).

The trials are testing a wide range of potential therapeutic strategies, with new pharmaceutical drugs listed beside thousand-year-old traditional therapies in the registry. Favilavir, an anti-viral drug, was the first approved COVID-19 drug in China. The drug reportedly showed efficacy in treating the disease with minimal side effects in a clinical trial involving 70 patients. Another trial underway in Shanghai is taking blood plasma from COVID-19 survivors and infusing it into patients who are still ill. This strategy is based on the idea that the antibodies of one person can be used to fight the virus in someone newly infected.

A trial in Shanghai is taking blood plasma from COVID-19 survivors and infusing it into patients who are still ill. This strategy is based on the idea that the antibodies of one person can be used to fight the virus in someone newly infected
Researchers are exploring answers outside of Western medicine, too. About 15 trials listed in the registry are testing a variety of traditional Chinese medicines, including Shuang Huang Lian, a Chinese herbal medicine that contains extracts from the dried fruit lianqiao (Forsythiae fructus), which has been used for treating infections for more than 2,000 years.

Clinical trials are also underway elsewhere in the world.

In Japan, two HIV antiretroviral drugs are being trialed to treat patients infected with COVID-19. These HIV drugs have reduced levels of related coronaviruses such as severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS). In the United States, another clinical trial led by the University of Nebraska Medical Centre is focusing on an anti-viral treatment called remdesivir, which was previously tested in humans with Ebola virus disease and has also shown promise in animals for MERS and SARS.

Here in Canada, the University of British Columbia’s Life Sciences Institute, in close cooperation with APEIRON Biologics AG, a Vienna-based biotechnology company, has launched a pilot clinical trial of APN01, a potential and novel treatment for COVID-19. The study is treating 24 patients in China with severe infection of SARS-CoV-2 to determine whether APN01 treatment improves outcomes.

Researching, Testing and Tracking COVID-19 in Canada
Canada’s experience with the SARS outbreak in 2003, combined with its strong public health system and leading infectious disease research community, make the country well prepared for the COVID-19 outbreak.

The Public Health Agency of Canada (PHAC) is working closely with partners domestically and around the world, including the WHO, to respond to this outbreak. Canadian infectious disease specialist with the B.C. Children’s Hospital, Dr. Srinivas Murthy, is serving as co-chair for the international WHO Clinical Research Committee, which is looking at why people get sick from the virus and how to help them recover.

The National Microbiology Laboratory (NML), with labs in Manitoba, Alberta, Ontario and Quebec, has developed diagnostic test that can quickly identify COVID-19 from clinical specimens. NML is working collaboratively with Canadian provincial public health laboratories to ensure there is additional testing capacity across the country. In addition, BlueDot, a Toronto based artificial intelligence firm, is working to help predict and track COVID-19 through human and artificial intelligence.

Last month, the Canadian Institutes for Health Research launched the Canadian 2019 Novel Coronavirus (COVID-19) Rapid Research Funding Opportunity competition (now closed) to enhance local, national and international collaborative efforts to mitigate the rapid spread of the illness. Findings and data from supported research projects must be shared internationally.

Canada’s experience with the SARS outbreak in 2003, combined with its strong public health system and leading infectious disease research community, make the country well prepared for the COVID-19 outbreak
Canada’s world-leading researchers in the areas of respiratory infectious disease and acute respiratory disease syndrome (ARDS) may also play an important role in our response to COVID-19 and future iterations of coronavirus. Researchers from St. Michael’s Hospital and Sunnybrook Hospital in Ontario are currently undertaking a wide variety of research including: measuring the burden of respiratory disease in Canada; determining the effectiveness and safety of different types of respiratory medication; and studying comorbidities that co-exist with common respiratory diseases. In addition, the Toronto ARDS Critical Illness Cell Therapy (TACCT) group is a network of respiratory and cardiovascular research programs (clinician and basic scientists) with an interest in cell therapies for ARDS. This network brings together experts in cell biology and genomics to conduct pre-clinical ARDS research and clinical trials. These two examples illustrate the importance of knowledge sharing and collaboration as we continue to search for new answers to combat COVID-19.

For the most up-to-date and accurate information about COVID-19 treatment, clinical trials and research, see the World Health Organization.

https://ottawacitizen.com/science/clini ... 4b77a6cfb3

[Bluemore]

https://www.klix.ba/vijesti/svijet/ital ... /200308067

Pratim
Jao kakav juris Pa ovo se treba pregladati vise puta
Ovo nije vidjeno!!!!!
Stvarno

[Bluemore]

Ako je istina, eto najvećeg problema. Bez obzira na uredbu, ljude ne zanima, a onda će kriviti vlade, zdravstvo, urote, samo sebe neće.

Pratim i ovo
Uredba je bila u najavi znaci nije na snazi
Ali Sta fali lupi

[breba]

https://www.klix.ba/vijesti/svijet/ital ... /200308067

Pratim
Jao kakav juris Pa ovo se treba pregladati vise puta
Ovo nije vidjeno!!!!!
Stvarno

Pa svi jos u voz pa ko zna kuda. Ovo im nije trebalo, ili zabraniti putovanje iz regije istog trenutka ili ne zatvarati uopste ali paziti ko putuje vez stvaranja panike. Sega stvarno.

[drag_gost]

svi poznati svjetski epidemiolozi govore o 70% zaraženih u svijetu
tako da je 29 miliona u US jos i malo

Ko su "svi poznati svjetski epidemiolozi"?
Dzaba navijas za masovno istrebljenje, nista od toga. Ljudski rod je pregrmio mnogo gore.

[Bluemore]

https://www.klix.ba/vijesti/svijet/ital ... /200308067

Pratim
Jao kakav juris Pa ovo se treba pregladati vise puta
Ovo nije vidjeno!!!!!
Stvarno

Pa svi jos u voz pa ko zna kuda. Ovo im nije trebalo, ili zabraniti putovanje iz regije istog trenutka ili ne zatvarati uopste ali paziti ko putuje vez stvaranja panike. Sega stvarno.

Da da svi
Sto ti je panika da da treba retroaktivno odredba da se primjeni
A Sta je do sada bilo te Sve uhvatiti i na lomacu
Nista pratim

[Jasna55]

svi poznati svjetski epidemiolozi govore o 70% zaraženih u svijetu
tako da je 29 miliona u US jos i malo

Ko su "svi poznati svjetski epidemiolozi"?
Dzaba navijas za masovno istrebljenje, nista od toga. Ljudski rod je pregrmio mnogo gore.

ne bi te ja dalje zadržavo
ostani u svom ubjeđenju

[drag_gost]

Nisam ni ocekivao odgovor koji zahtjeva razmisljanje.
Dzaba si se registrovao.

[GAU8]

A ti vec znas da ce biti 29 miliona zarazenih. Boze sacuvaj, kao da navijas.

Ne navija već stavlja broj umrlih od influenca virusa u omjer sa brojem zaraženih od influenca virusa.

[sve_ovo_ja]

svi poznati svjetski epidemiolozi govore o 70% zaraženih u svijetu
tako da je 29 miliona u US jos i malo

Ko su "svi poznati svjetski epidemiolozi"?
Dzaba navijas za masovno istrebljenje, nista od toga. Ljudski rod je pregrmio mnogo gore.

ne bi te ja dalje zadržavo
ostani u svom ubjeđenju

Valjda zadržavala, zar ti nisi Jasna?
Jasna, Jasna, nikad mi nećeš biti jasna...

Samo report ovakve klonove.

[Leverage]

Jao koji isfur

[arman1]

svi poznati svjetski epidemiolozi govore o 70% zaraženih u svijetu
tako da je 29 miliona u US jos i malo

Ko su "svi poznati svjetski epidemiolozi"?
Dzaba navijas za masovno istrebljenje, nista od toga. Ljudski rod je pregrmio mnogo gore.

ne bi te ja dalje zadržavo
ostani u svom ubjeđenju

Jasna ???

[armin071]

Jasna “mutira(o)la”

[kakavdanakneiskustvu]

sad cu u nick staviti zensko ime, nece me otkriti 100%

[TheRealist]

Pratim i ovo
Uredba je bila u najavi znaci nije na snazi
Ali Sta fali lupi

Da, u najavi, zdrav mozak kažeš da ostaneš, ne da bježiš. Ima razlog zašto se išlo sa tom strategijom, ali ljude uglavnom nije baš briga.

[drag_gost]

Jasna “mutira(o)la”

Jasna je iznenada postao jasan.

[kakavdanakneiskustvu]

https://www.klix.ba/sport/nogomet/nogom ... /200308109

[Chmoljo]

https://www.klix.ba/vijesti/svijet/ital ... /200308067

Pratim
Jao kakav juris Pa ovo se treba pregladati vise puta
Ovo nije vidjeno!!!!!
Stvarno

Jel ovo opet ratuju protiv Grka?

[omar little]

juzna koreja hendla situaciju da stanes i zines.

[JanuaryJones]

juzna koreja hendla situaciju da stanes i zines.

Elaboriraj

[Zox]

U njemackoj i dalje nema smrtnih slucajeva, zato mi nikako nije jasno zasto je ovakav haos u italiji, je li moguce da im je zdravstveni sistem tako los?

U stvari, u Lombardiji (koja je zariste) je vrlo dobar zdravstveni sistem. Puno bolji od ostatka Italije, gdje ce TEK nastati haos kad se prosiri.
Nije ni do starije populacije, u Njemackoj je skoro jednako stara.
U ovom trenutku, i Italijani pokusavaju ocajnicki da shvate sto je bas kod njih ovolika smrtnost.

[TheRealist]

Pa znaju, koliko znam. Bolest počela u bolnici, prenosili i pacijenti i osoblje. Tu rizična populacija i automatski velika smrtnost.

Osim toga, oni valjda ne testiraju puno, tačnije samo teže pacijente testiraju i one sa naglašenijim simptomima, jer nemaju vremena, ni kapaciteta za ostale (kako im je zahvatilo rizičnu populaciju, intenzivne njege su prezauzete), tako da je procenat smrtnosti ipak manji (ovo je bitno radi nekih procjena, naravno da je i dalje grozno za one koji su izgubili nekoga)!

[Tempo]

samo genetika. nista drugo ne moze biti razlog.

[Tempo]

u tom kontekstu, vidim da virus, bar za sad, ne jebe slavene. to bi mogao biti dobar znak za nas.
ukupno 110 slucajeva u cijelom varsavskom paktu i jugoslaviji.

[omar little]

juzna koreja hendla situaciju da stanes i zines.

Elaboriraj

odgovoran i ozbiljan pristup od samog pocetka. agresivno testiranje, najorganiziranije na planeti. testiraju za korona virus kao sto amerikanci prodaju hamburgere. preko 180,000 ljudi su testirali za malo vise od dva tjedna (cini mi se da je kod njih krenulo 24-25-26 februar). za sada imaju slucajeva kao italija i 50 mrtvih. dezinficiraju grad, javni prevoz, trzisne centre, aerodrome. nema velikih okupljanja. stanovnistvo se ne vozika po javnom prevozu ako ne mora. zabranili izvoz maski i podebljali proizvodnju zastitne opreme. propagiraju distancu i rad od kuce koliko god je moguce. vlada gura social distancing kampanju. jos vidjeh da su najavili da ce tuziti sektu zbog koje je buknuo virus ovako u daegu. (da se mene pita ja bi ih zabranila za sva vremena. )



Latest News (8th March)
Current cases: 7313. Current Deaths: 50. Source

Cases today have increased to 7313. Out of this total, Daegu makes up 5378 (73.5% of Korea’s total cases). In more positive news though, this is the lowest number of new cases reported in a single day since February 26th. Further, this is the first time in 11 days that the day case gain has been less than 400.

Although it’s too early to make a call, it appears like the strong containment actions taken by the government may be working. We will have to wait and see the trends over the next few days and weeks, however.

Many experts support this view, with some saying that it is too early to say the spread is slowing. Testing capacity has also been increased to 17,000 , a staggering amount.

Perhaps expectedly, it has also been found that public transport users in Seoul have dropped around 35% from the daily average in January. This is a good sign, as it shows that people are staying away from crowded transport and possibly helping to contain the virus.

Many soldiers from around the country have been called to help fight the virus. From military doctors to soldiers, the military is helping in all kinds of ways.