vec sam ti tamo stavila granicnu vrijednost, vjerovatno nisi primjetila...otherside wrote: Considering a risk of 1:386 as the borderline between high risk and lower risk means that the predictive power of the screening test is not 100% absolute, and there is a possibility that children with Down syndrome will be born to a certain percentage of women despite the result of the screening test having been regarded as "normal". On the other hand, there is a more common situation in which a woman receives an "abnormal" result in a screening test, only for the fetus to be found to be normal in prenatal testing (chorionic villus sampling or amniocentesis) performed subsequently. Essentially, approximately 98% of women who receive an abnormal result in the screening test have healthy fetuses. Despite these limitations, a risk group can be reliably defined using this test. Performing amniocentesis on women in the high-risk group has often prevented the birth of infants with chromosomal defects.
It should be noted that the biochemical screening tests can also indicate conditions apart from Down syndrome - for instance other chromosomal problems, defects of the closure of the spinal column, kidney defects, etc.
evo sad sam boldirala.
