Škobo Habu wrote:Vi ste svi zaglibili sa Freudom i Jungom.Connaisseur Karlin wrote:
seks dolazi iz glave![]()
svima se isto dize , heterosima ili heomosima
znaci, seksulana orijentacija je diefinivno psiholoski obojena
Savremena medicina je nakon njih uznapredovala divovskim koracima, te neka istraživanja potvrđuju da postoje i genetske predispozicije po pitanju seksualne orijentacije.
http://znano.st/znanost-zdravnje-i-medi ... avlje/1562
https://www.nature.com/articles/s41598- ... 4#ref-CR22Male sexual orientation is moderately heritable (30~40%), but is multifactorial, with evidence of multiple genetic and environmental contributions, via family studies6,7,8,9,10,11, twin studies4,12,13,14,15,16, and segregation analyses8,10,11,17. Although focused (i.e., chromosome X) and genome-wide linkage studies (GWLS) of affected (i.e., concordant) sibling pairs have been applied to the trait8,18,19,20,21,22, these have been in relatively small samples prior to our own GWLS23, which showed genome-wide significant linkage to the pericentromeric region of chromosome 8 and strong support for linkage to the previously reported Xq28 region. Although genetic variant(s) contributing to development of male sexual orientation have been mapped to pericentromeric chromosome 8 and chromosome Xq28, the linkage peaks are large and specific trait genes have not been identified.
To date, there have been four X-chromosome linkage studies of male sexual orientation (Fig. 1). Hamer et al.(1) analyzed 40 pairs of gay brothers and found that they shared 82% of their alleles in the Xq28 region; this was greater than the 50% allele sharing that would be expected by chance (p = 0.00001). In a follow-up study, Hu et al. (5) analyzed an independent series of 32 genetically informative pairs of gay brothers and found 67% allele sharing (p = 0.04). Hu et al. also found that the heterosexual brothers of Xq28-concordant gay sib-pairs had only a 22% likelihood of carrying the same Xq28 allele; this independent test of linkage was statistically significant (p < 0.05), giving an overall significance level of p = 0.004 for their study. In 1998, the independent research group of Sanders et al.(6) reported the results of an X chromosome linkage analysis of 54 pairs of gay brothers. They found 66% Xq28 allele sharing (p = 0.04). The results of the study by Sanders et al. were indistinguishable from those in the study by Hu et al., both in terms of the degree of allele sharing (66% versus 67%) and the precise chromosomal location of maximum sharing (locus DXS1108). By contrast, Rice et al. (2) studied 52 pairs of gay brothers and found no evidence for linkage to Xq28; they reported approximately 46% allele sharing, a nonsignificant result.
https://science.sciencemag.org/content/285/5429/803We agree with Hamer that our results do not exclude the possibility of genetic effects underlying male homosexuality. But with the use of similiar methods of family ascertainment, phenotyping, and genotyping, we were unable to confirm evidence for an Xq28-linked locus underlying male homosexuality. Sanders et al. (3) came to the same conclusion with their linkage study.
The basis of sexual orientation remains uncertain, but the pathways involved can be expected to be complex. The controversies and methodological difficulties notwithstanding, the study of sexual orientation contains fascinating riddles, and further careful systematic study has the potential to reveal important insights about who we are.
